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Anti -LMX1b Rabbit PAb Immunohistochemical Immunofluorescence Primary Antibody

Specification: 100uL
  • GB11744
  • Servicebio
  • Servicebio

Description

Product Information


Description

LMX1b rabbit polyclonal

Protein full name

LIM homeobox transcription factor 1-beta

Synonyms

LMX1B, LMX1.2, NPS1, LIM homeobox transcription factor 1 beta

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse LMX1b

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

O88609




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 500-1: 1000

lung, skeletal muscle,

heart muscle

IF

Mouse, Rat

1: 250-1: 500

lung, skeletal muscle,

heart muscle




Background


LMX1B is a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. This protein is a LIM homeobox transcription factor which plays a central role in dorso-ventral patterning of the vertebrate limb, which is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome.




Images



图片 1.png

Immunohistochemistry analysis of paraffin-embedded mouse lung using

LMX1b (GB11744) at dilution of 1: 500


image.png

Immunohistochemistry analysis of paraffin-embedded rat skeletal muscle  using LMX1b (GB11744) at dilution of 1: 500

image.png

Immunohistochemistry analysis of paraffin-embedded rat heart muscle using LMX1b (GB11744) at dilution of 1: 500




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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