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Anti -NFkB Inducing Kinase NIK Rabbit pAb Western Blot Antibodies

Specification: 100uL
  • GB11768
  • Servicebio
  • Servicebio

Description

Product Information


Description

NFkB Inducing Kinase NIK rabbit polyclonal

Protein full name

Mitogen-activated protein kinase kinase kinase 14

Synonyms

MAP3K14, FTDCR1B, HS, HSNIK, NIK, Mitogen-activated protein kinase, kinase, kinase 14, Map3k14

Immunogen

Recombinant protein corresponding to Mouse MAP3K14

Isotype

IgG

Purity

Affinity purification

Predicted MW.

104 kDa

Observed MW.

104 kDa

Uniprot ID

Q99558




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human

1: 500-1: 1000

A549, HeLa, HepG2




Background


Mitogen-activated protein kinase kinase kinase 14 also known as NF-kappa-B-inducing kinase (NIK) is an enzyme encoded by the MAP3K14 gene. This protein is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-κB activity. It is a critical kinase of the alternative NF-κB activation pathway. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-κB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.




Images



image.png

Western blot analysis of MAP3K14

(GB11768) at dilution of 1: 1000

Lane 1: A549 cell lysate

Lane 2: HeLa cell lysate

Lane 3: HepG2 cell lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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