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Anti -Ionotropic Glutamate Receptor 2 Rabbit PAb Immunohistochemistry Immunofluorescence Primary Antibody

Specification: 100uL
  • GB11770
  • Servicebio
  • Servicebio

Description

Product Information


Description

Ionotropic Glutamate receptor 2

rabbit polyclonal

Protein full name

Glutamate receptor 2

Synonyms

Gria2, GRIA2, GLUR2, GLURB, GluA2, GluR-K2, HBGR2, Glutamate ionotropic receptor AMPA type subunit 2

Immunogen

Recombinant protein corresponding to Mouse GRIA2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membran, Cytoplasm

Uniprot ID

P23819, P19491




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 500-1: 1000

brain

IF

Mouse, Rat

1: 250-1: 500

brain




Background


Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.




Images



image.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using

GRIA2 (GB11770) at dilution of 1: 500


image.png

Immunohistochemistry analysis of paraffin-embedded rat brain using

GRIA2 (GB11770) at dilution of 1: 500





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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