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Anti -Alpha-synuclein Rabbit PAb for Western Blot WB Antibody

Specification: 100uL
  • GB11773
  • Servicebio
  • Servicebio

Description

Product Information


Description Alpha-synuclein rabbit polyclonal
Protein full name Alpha-synuclein
Synonyms Snca, α-synuclein, SNCA, NACP, PARK1, PARK4, PD1, synuclein alpha
Immunogen Recombinant protein corresponding to Mouse α-synuclein
Isotype IgG
Purity Affinity purification
Predicted MW. 14 kDa
Observed MW. 19 kDa
Uniprot ID O55042, P37377




Applications


Applications Species Dilution Positive Tissue
WB Mouse, Rat 1: 500-1: 1000 cerebral cortex, brain,
cerebellum, spinal cord




Background




Alpha-synuclein is a protein that, in humans, is encoded by the SNCA gene. It is abundant in the brain while smaller amounts are found in the heart, muscles, and other tissues. In the brain, alpha-synuclein is found mainly at the tips of nerve cells (neurons) in specialized structures called presynaptic terminals. Within these structures, alpha-synuclein interacts with phospholipids and proteins. Presynaptic terminals release chemical messengers, called neurotransmitters, from compartments known as synaptic vesicles. The release of neurotransmitters relays signals between neurons and is critical for normal brain function.




Images



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Western blot analysis of α-synuclein (GB11773) at dilution of 1: 1000

Lane 1: Mouse cerebral cortex tissue lysate

Lane 2: Mouse brain tissue lysate

Lane 3: Mouse cerebellum tissue lysate

Lane 4: Mouse spinal cord tissue lysate

Lane 5: Rat cerebral cortex tissue lysate

Lane 6: Rat brain tissue lysate

Lane 7: Rat cerebellum tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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