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Anti -Raf1 Rabbit PAb Protein Detection Western Blot Antibodies

Specification: 100uL
  • GB11780
  • Servicebio
  • Servicebio

Description

Product Information


Description

Raf1 rabbit polyclonal

Protein full name

RAF proto-oncogene serine/threonine-protein kinase

Synonyms

Raf1, RAF1, Raf-1 proto-oncogene, serine/threonine kinase, CMD1NN, CRAF, NS5, c-Raf

Immunogen

KLH conjugated Synthetic peptide corresponding to Human Raf1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

73 kDa

Observed MW.

73 kDa

Uniprot ID

P04049, Q99N57, P11345




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1500

muscle, testis, ovary




Background



RAF proto-oncogene serine/threonine-protein kinase, also known as proto-oncogene c-RAF or simply c-Raf or even Raf-1, is an enzyme[4] that in humans is encoded by the RAF1 gene. The c-Raf protein is part of the ERK1/2 pathway as a MAP kinase kinase kinase (MAP3K) that functions downstream of the Ras subfamily of membrane associated GTPases. C-Raf is a member of the Raf kinase family of serine/threonine-specific protein kinases, from the TKL (Tyrosine-kinase-like) group of kinases.




Images



image.png

Western blot analysis of Raf1 (GB11780)

at dilution of 1: 1000

Lane 1: A549 cell lysate

Lane 2: SW480 cell lysate

Lane 3: Jurkat cell lysate

Lane 4: Mouse muscle tissue lysate

Lane 5: Mouse testis tissue lysate

Lane 6: Mouse ovary tissue lysate

Lane 7: Rat muscle tissue lysate

Lane 8: Rat testis tissue lysate

Lane 9: Rat ovary tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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