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Anti -TBR1 Rabbit PAb for Immunohistochemistry Immunofluorescence Primary Antibody

Specification: 100uL
  • GB11785
  • Servicebio
  • Servicebio

Description

Product Information



Description

TBR1 rabbit polyclonal

Protein full name

T-box brain protein 1

Synonyms

TBR1, TBR-1, TES-56, T-box, brain 1, IDDAS

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse TBR1

Isotype IgG
Purity Affinity purification
Subcellular location

Nucleus

Uniprot ID

Q64336




Applications



Applications

IHC

IF

Species

Mouse, Rat

Mouse, Rat

Dilution

1: 500-1: 1000

1: 250-1: 500

Positive tissue

substantia nigra, hippocampus

substantia nigra, hippocampus




Background


T-box, brain, 1 is a transcription factor protein important in vertebrate embryo development encoded by the TBR1 gene. TBR1 is a member of the TBR1 subfamily of T-box family transcription factors, which share a common DNA-binding domain. Other members of the TBR1 subfamily include EOMES and TBX21. TBR1 is involved in the differentiation and migration of neurons and is required for normal brain development. TBR1 interacts with various genes and proteins in order to regulate cortical development, specifically within layer VI of the developing six-layered human cortex. Studies show that TBR1 may play a role in major neurological diseases such as Alzheimer's Disease (AD) and Parkinson's Disease (PD).




Images



image.png

Immunohistochemistry analysis of paraffin-embedded mouse s bstantia nigra using TBR1 (GB11785) at dilution of 1: 500

image.png

Immunohistochemistry analysis of paraffin-embedded rat hippocampus using TBR1 (GB11785) at dilution of 1: 500




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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