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Anti -p95 NBS1 Rabbit PAb for Immunohistochemistry Immunofluorescence Primary Antibody

Specification: 100uL
  • GB11794
  • Servicebio
  • Servicebio

Description

Product Information


Description

p95 NBS1 rabbit polyclonal

Protein full name

Nibrin

Synonyms

Nbn, NBN, AT-V1, AT-V2, ATV, NBS, NBS1, P95, nibrin

Immunogen

Recombinant protein corresponding to Mouse NBS1

Isotype IgG
Purity Affinity purification
Subcellular location

Nucleus

Uniprot ID

Q9R207, Q9JIL9




Applications



Applications

IHC

IF

Species

Mouse, Rat

Mouse, Rat

Dilution

1: 1000-1: 2000

1: 500-1: 1000

Positive tissue

kidney, testis, heart

kidney, testis, heart




Background




Nibrin is a protein associated with the repair of double strand breaks (DSBs) which pose serious damage to a genome. It is a 754 amino acid protein identified as a member of the NBS1/hMre11/RAD50(N/M/R, more commonly referred to as MRN) double strand DNA break repair complex. This complex recognizes DNA damage and rapidly relocates to DSB sites and forms nuclear foci. It also has a role in regulation of N/M/R (MRN) protein complex activity which includes end-processing of both physiological and mutagenic DNA double strand breaks (DSBs).




Images



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Immunohistochemistry analysis of paraffin-embedded mouse kidney using NBS1 (GB11794) at dilution of 1: 1000

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Immunohistochemistry analysis of paraffin-embedded rat kidney using NBS1 (GB11794) at dilution of 1: 1000

image.png

Immunohistochemistry analysis of paraffin-embedded mouse testis using NBS1 (GB11794) at dilution of 1: 1000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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