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Anti -MAPK11 Rabbit PAb for Protein Detection Western Blot Antibodies

Specification: 100uL
  • GB11811
  • Servicebio
  • Servicebio

Description

Product Information


Description MAPK11 rabbit polyclonal
Protein full name Mitogen-activated protein kinase 11
Synonyms Mapk11, MAPK11, P38B, P38BETA2, PRKM11, SAPK2, SAPK2B, p38-2, p38Beta, mitogen-activated protein kinase 11
Immunogen Recombinant protein corresponding to
Mouse MAPK11
Isotype IgG
Purity Affinity purification
Subcellular location Nucleus, Cytoplasm
Predicted MW. 42 kDa
Observed MW. 42 kDa
Uniprot ID Q9WUI1




Applications


Applications Species Dilution Positive Tissue
WB Mouse, Rat 1: 500-1: 1500 heart, brain




Background


Mitogen-activated protein kinase 11 is an enzyme encoded by the MAPK11 gene. The protein is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.




Images



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Western blot analysis of MAPK11 (GB11811) at dilution of 1: 1000

Lane 1: Mouse heart tissue lysate

Lane 2: Mouse brain tissue lysate

Lane 3: Rat heart tissue lysate

Lane 4: Rat brain tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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