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Anti -ATF-4 Rabbit PAb for Western Blot

Specification: 100uL
  • GB11813
  • Servicebio
  • Servicebio

Description

Product Information


Description

ATF-4 rabbit polyclonal

Protein full name

Cyclic AMP-dependent transcription factor ATF-4

Synonyms

cAMP-dependent transcription factor ATF-4, Activating transcription factor 4, C/EBP-related ATF, C/ATF, TaxREB67 homolog, Atf4

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse ATF-4

Isotype

IgG

Purity

Affinity purification

Predicted MW.

38 kDa

Observed MW.

45 kDa

Uniprot ID

Q06507, Q9ES19




Applications



Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

brain, retina




Background



Activating transcription factor 4 (tax-responsive enhancer element B67), also known as ATF4, is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The protein is  characterized as the cAMP-response element binding protein 2 (CREB-2) and belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. ATF4 transcription factor is also known to play role in osteoblast differentiation along with RUNX2 and osterix.




Images



image.png

Western blot analysis of ATF-4

(GB11813) at dilution of 1: 1000

Lane 1: Mouse brain tissue lysate

Lane 2: Mouse retina tissue lysate

Lane 3: Rat brain tissue lysate

Lane 4: Mouse retina tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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