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Anti -FLIP Rabbit pAb Polyclonal antibody for Western Blot

Specification: 100uL
  • GB11817
  • Servicebio
  • Servicebio

Description

Product Information



Description

FLIP rabbit polyclonal

Protein full name

CASP8 and FADD-like apoptosis regulator

Synonyms

CASH, Cflar, CFLAR, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, CASP8 and FADD like apoptosis regulator

Immunogen

Recombinant protein corresponding to Mouse FLIP

Isotype IgG
Purity Affinity purification

Predicted MW.

55 kDa

Observed MW.

55 kDa

Uniprot ID

O15519, O35732




Applications



Applications

WB

Species

Human, Mouse, Rat

Dilution

1: 500-1: 1000

Positive tissue

kidney, heart




Background



CASP8 and FADD-like apoptosis regulator is a protein encoded by the CFLAR gene. It is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.




Images



image.png

Western blot analysis of FLIP (GB11817) at dilution of 1: 1000

Lane 1: HT-29 cell lysate

Lane 2: C2C12 cell lysate

Lane 3: Jurkat cell lysate

Lane 4: A431 cell lysate

Lane 5: NIH/3T3 cell lysate

Lane 6: Mouse heart tissue lysate

Lane 7: Mouse kidney tissue lysate

Lane 8: Rat heart tissue lysate

Lane 9: Rat kidney tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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