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Anti -TNNC1 Rabbit pAb Western Blot Protein detection antibody

Specification: 100uL
  • GB11824
  • Servicebio
  • Servicebio

Description

Product Information


Description

TNNC1 rabbit polyclonal

Protein full name

Troponin C, slow skeletal and cardiac muscles

Synonyms

Tnnc1, TNNC1, CMD1Z, CMH13, TN-C, TNC, TNNC, Troponin C type 1, Troponin C1, Slow skeletal and cardiac type

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse TNNC1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

18 kDa

Observed MW.

18 kDa

Uniprot ID

P19123




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse

1: 500-1: 1500

heart, muscle, kidney




Background




Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).




Images



image.png

Western blot analysis of TNNC1

(GB11824) at dilution of 1: 1000

Lane 1: Mouse heart tissue lysate

Lane 2: Mouse muscle tissue lysate

Lane 3: Mouse kidney tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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