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Anti -beta TRCP2/HOS Rabbit pAb for Immunohistochemistry immunofluorescence

Specification: 100uL
  • GB11827
  • Servicebio
  • Servicebio

Description

Product Information



Description

β-TRCP2 rabbit polyclonal

Protein full name

F-box/WD repeat-containing protein 11

Synonyms

Fbxw11, FBXW11, BTRC2, BTRCP2, FBW1B, FBXW1B, Fbw11, Hos, F-box and WD repeat domain containing 11, β-TRCP2

Immunogen

Recombinant protein corresponding to

Mouse β-TRCP2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm

Uniprot ID

Q9UKB1




Applications



Applications

Species

Dilution

Positive Tissue

IHC

Human

1: 300-1: 600

liver cancer, thyroid,

mammary gland

IF

Human

1: 150-1: 300

liver cancer, thyroid,

mammary gland




Background




βTrCP2 (beta-transducin repeat containing protein 2; also known as Fbxw11 or HOS) is a protein encoded by the FBXW11 gene. The protein is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation -dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbws class and in addition to an F-box, contains multiple WD40 repeats.




Images



image.png

Immunohistochemistry analysis of paraffin-embedded human liver cancer using

β-TRCP2 (GB11827) at dilution of 1: 500


image.png

Immunohistochemistry analysis of paraffin-embedded human thyroid using

β-TRCP2 (GB11827) at dilution of 1: 500


image.png

Immunohistochemistry analysis of paraffin-embedded human mammary gland using β-TRCP2 (GB11827) at dilution of

1: 500





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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