PHONE

+86(027) 5111 3188

Share to:

Anti -Carma 1 / CARD11 Rabbit PAb for Immunohistochemistry Immunofluorescence

Specification: 100uL
  • GB11828
  • Servicebio
  • Servicebio

Description

Product Information



Description

CARD11 rabbit polyclonal

Protein full name

Caspase recruitment domain-containing protein 11

Synonyms

Card11, CARD11, BENTA, BIMP3, CARMA1, IMD11, PPBL, Caspase recruitment domain family member 11, IMD11A

Immunogen

Recombinant protein corresponding to

Mouse CARD11

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm

Uniprot ID

Q8CIS0




Applications



Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 300-1: 600

colon, pneumonia, spleen, enteritis, brain

IF

Mouse, Rat

1: 150-1: 300

colon, pneumonia, spleen, enteritis, brain




Background




Caspase recruitment domain-containing protein 11 is a protein encoded by the CARD11 gene. The protein belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.




Images



image.png

Immunohistochemistry analysis of paraffin-embedded human colon using

CARD11 (GB11828) at dilution of 1: 300


image.png

Immunohistochemistry analysis of paraffin-embedded mouse pneumonia

using CARD11 (GB11828) at dilution of 1: 300


image.png

Immunohistochemistry analysis of paraffin-embedded rat spleen using

CARD11 (GB11828) at dilution of 1: 300


image.png

Immunohistochemistry analysis of paraffin-embedded rat enteritis using

CARD11 (GB11828) at dilution of 1: 300


image.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using

CARD11 (GB11828) at dilution of 1: 300





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

downLoadImgLaboratory(1)Slice 13Slice 10Slice 12

Contact us

Quick Links

Product Category

Get In Touch

 5th Floor, 22 Building, Biopark, Gaoxin 2nd Road No. 388, East Lake High-Tech Developing Zone, Wuhan, Hubei, China 430079
 +86(027) 5111 3188
Copyright © 2021  Wuhan Servicebio Technology Co., Ltd.