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Anti -Paxillin Rabbit pAb

  • Servicebio

Description

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Product Information

Description

Paxillin rabbit polyclonal

Protein full name

Paxillin

Synonyms

Pxn, PXN, Entrez:5829, Paxillin, PXN protein, Paired box protein Pax 1, PAX1, Paxillin alpha

Immunogen

Recombinant protein corresponding to Mouse Paxillin

Isotype

IgG

Purity

Affinity purification

Predicted MW.

65 kDa

Observed MW.

72 kDa

Uniprot ID

P49023, Q8VI36, Q66H76



Applications

Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 20000-1: 50000

spleen, lung, testis



Background

Paxillin is a protein encoded by the PXN gene. Paxillin is a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Mutations in PXN as well as abnormal expression of paxillin protein has been implicated in the progression of various cancers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.


Images

图片 1.png


Western blot analysis of Paxillin

(GB11831) at dilution of 1: 1000

Lane 1: Hela cell lysate

Lane 2: MCF7 cell lysate

Lane 3: NIH3T3 cell lysate

Lane 4: Mouse spleen tissue lysate

Lane 5: Mouse lung tissue lysate

Lane 6: Mouse testis tissue lysate

Lane 7: Rat spleen tissue lysate

Lane 8: Rat lung tissue lysate

Lane 9: Rat testis tissue lysate



Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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