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Anti - PKC beta 2 Rabbit pAb

  • Servicebio

Description

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Product Information

Description

PKC beta 2 rabbit polyclonal

Protein full name

Protein kinase C beta type

Synonyms

Prkcb, rotein Kinase C, KPCB, PKC Beta, PKC-B, PRKCB II, PRKCB2, Protein kinase C beta, Protein kinase C beta type, PKC-β2

Immunogen

Recombinant protein corresponding to

Mouse PKC-β2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

P68404



Applications

Applications

Species

Dilution

Positive Tissue

IHC

Mouse

1: 1500-1: 3000

brain, cerebellum

IF

Mouse

1: 750-1: 1500

brain, cerebellum



Background

Protein kinase C (PKC) is a family of serine and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption.


Images

image.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using

PKC-β2 (GB11833) at dilution of 1: 3000


image.png

Immunohistochemistry analysis of paraffin-embedded mouse cerebellum

using PKC-β2 (GB11833) at dilution of 1: 3000



Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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