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Anti -GSK3 beta Rabbit pAb

  • Servicebio

Description

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Product Information

Description

GSK3 beta rabbit polyclonal

Protein full name

Glycogen synthase kinase-3 beta

Synonyms

GSK3B, Gsk3b, 7330414F15Rik, 8430431H08Rik, C86142, GSK-3, GSK-3beta, GSK3, glycogen synthase kinase 3 beta

Immunogen

Recombinant protein corresponding to Mouse GSK3β

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus, Cell membrane

Uniprot ID

P49841, Q9WV60



Applications

Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 1000-1: 2000

ovary, brain, colon,

breast carcinoma

IF

Mouse, Rat

1: 500-1: 1000

ovary, brain, colon,

breast carcinoma



Background

Glycogen synthase kinase-3 (GSK-3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and an inactivating agent of glycogen synthase. Two isoforms, alpha (GSK3A) and beta, show a high degree of amino acid homology. GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation. It might be a new therapeutic target for ischemic stroke.


Images

image.png

Immunohistochemistry analysis of paraffin-embedded mouse ovary using

GSK3β(GB11835) at dilution of 1: 1500


image.png

Immunohistochemistry analysis of paraffin-embedded mouse colon using

GSK3β(GB11835) at dilution of 1: 1500


image.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using

GSK3β(GB11835) at dilution of 1: 1500


image.png

Immunohistochemistry analysis of paraffin-embedded rat brain using

GSK3β(GB11835) at dilution of 1: 1500


image.png

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma using GSK3β(GB11835) at dilution of 1: 1500



Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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