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Anti -RbAp46 Rabbit pAb

  • Servicebio

Description

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Product Information

Description

RbAp46 rabbit polyclonal

Protein full name

Histone-binding protein RBBP7

Synonyms

Rbbp7, RBBP7, RbAp46, Retinoblastoma binding protein 7, RB binding protein 7, Chromatin remodeling factor

Immunogen

Recombinant protein corresponding to

Mouse RbAp46

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

Q16576, Q60973, Q71UF4



Applications

Applications

Species

Dilution

Positive Tissue

IHC

Human, Mouse, Rat

1: 1000-1: 2000

colon, colon cancer, uterrus, muscle, ovary,

kidney, brain

IF

Human, Mouse, Rat

1: 500-1: 1000

colon, colon cancer, uterrus, muscle, ovary,

kidney, brain



Background

Histone-binding protein RBBP7 is a protein encoded by the RBBP7 gene.

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including msin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation.


Images

image.png

Immunohistochemistry analysis of paraffin-embedded human colon using

RbAp46 (GB11836) at dilution of 1: 1000


image.png

Immunohistochemistry analysis of paraffin-embedded human colon cancer

using RbAp46 (GB11836) at dilution of 1:1000


image.png

Immunohistochemistry analysis of paraffin-embedded mouse uterrus using

RbAp46 (GB11836) at dilution of 1: 1000


image.png

Immunohistochemistry analysis of paraffin-embedded mouse muscle using

RbAp46 (GB11836) at dilution of 1: 1000


image.png

Immunohistochemistry analysis of paraffin-embedded rat ovary using

RbAp46 (GB11836) at dilution of 1: 1000


image.png

Immunohistochemistry analysis of paraffin-embedded mouse kidney using

RbAp46 (GB11836) at dilution of 1: 1000


image.png

Immunohistochemistry analysis of paraffin-embedded rat kidney using

RbAp46 (GB11836) at dilution of 1: 1000


image.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using

RbAp46 (GB11836) at dilution of 1: 1000


image.png

Immunohistochemistry analysis of paraffin-embedded rat brain using

RbAp46 (GB11836) at dilution of 1: 1000



Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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