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Anti -MOG Rabbit pAb

  • Servicebio

Description

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Product Information

Description

MOG rabbit polyclonal

Protein full name

Ran guanine nucleotide release factor

Synonyms

MOG1, MOG 1, MOG1 homolog, Ran guanine nucleotide release factor, Ran-binding protein MOG1, RanGNRF, RANGRF, MOG

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse MOG

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm

Uniprot ID

Q9JIB0 , Q9HD47



Applications

Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 1000-1: 3000

testis

IF

Mouse, Rat

1: 500-1: 1500

testis



Background

This gene encodes a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1.5 cardiac sodium channel in human. Alternative splicing results in multiple transcript variants. May regulate the intracellular trafficking of RAN. Promotes guanine nucleotide release from RAN and inhibits binding of new GTP by preventing the binding of the RAN guanine nucleotide exchange factor RCC1. Regulates the levels of GTP-bound RAN in the nucleus, and thereby plays a role in the regulation of RAN-dependent mitotic spindle dynamics (By similarity). Enhances the expression of SCN5A at the cell membrane in cardiomyocytes.


Images

image.png

Immunohistochemistry analysis of paraffin-embedded mouse tumor using

MOG (GB11850) at dilution of 1: 1500


image.png

Immunohistochemistry analysis of paraffin-embedded mouse tumor using

MOG (GB11850) at dilution of 1: 1500



Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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