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Anti -Egr1 Rabbit pAb

  • Servicebio

Description

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Product Information

Description

EGR1 rabbit polyclonal

Protein full name

Early growth response protein 1

Synonyms

EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225, Early growth response 1

Immunogen

Recombinant protein corresponding to Mouse EGR1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm

Predicted MW.

57 kDa

Observed MW.

57 kDa

Uniprot ID

P08046, P18146, P08154



Applications

Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

liver, uterus, testis

IHC

Mouse, Rat

1: 1500-1: 3000

brain

IF

Mouse, Rat

1: 750- 1: 1500

brain



Background

EGR-1 (Early growth response protein 1) is a protein encoded by the EGR1 gene. The protein belongs to the EGR family of Cys2His2-type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentiation and mitogenesis. Studies suggest this is a tumor suppressor gene. It has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity. EGR-1 has also been found to regulate the expression of VAMP2.


Images

image.png

Western blot analysis of EGR1

(GB11853) at dilution of 1: 1000

Lane 1: 293T cell lysate

Lane 2: Mouse liver tissue lysate

Lane 3: Mouse uterus tissue lysate

Lane 4: Mouse testis tissue lysate

Lane 5: Rat liver tissue lysate

Lane 6: Rat uterus tissue lysate

Lane 7: Rat testis tissue lysate


image.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using

EGR1 (GB11853)at dilution of 1: 1500


image.png

Immunohistochemistry analysis of paraffin-embedded rat brain using

EGR1 (GB11853) at dilution of 1: 1500



Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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