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OAnti -Myt1 Rabbit pAb

  • Servicebio

Description

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Product Information

Description

Myt1 rabbit polyclonal

Protein full name

Myelin transcription factor 1

Synonyms

MYT 1,Myt1, Myt 1, MTF1, MYTI, NZF2, PLPB1, ZC2HC4A, ZC2H2C1, Myelin transcription factor 1, Proteolipid protein-binding protein

Immunogen

Recombinant protein corresponding to Mouse Myt1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

124 kDa

Observed MW.

124 kDa

Uniprot ID

Q01538, Q8CFC2



Applications

Applications

Species

Dilution

Positive Tissue

WB

Human

1: 500-1: 1000

Jurkat, U87,

U251, SH-SY5Y



Background

Myelin transcription factor 1 is a protein encoded by the MYT1 gene. Myt1 is a zinc finger protein that is known to interact with the co-repressor Sin3B and also HDAC1 and HDAC2. Myt1 binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription.


Images

image.png

Western blot analysis of Myt1

(GB11854) at dilution of 1: 800

Lane 1: Jurkat cell lysate

Lane 2: U87 cell lysate

Lane 3: U251 cell lysate

Lane 4: SH-SY5Y cell lysate



Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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