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Anti -Dynamin 1 Rabbit pAb

  • Servicebio

Description

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Product Information

Description

Dynamin 1 rabbit polyclonal

Protein full name

Dynamin-1

Synonyms

DNM1, DNM 1, Dynamin-1, DNM, EIEE31, Dynamin1, Dynamin 1, Dynamin

Immunogen

Recombinant protein corresponding to Mouse Dynamin 1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoskeleton

Predicted MW.

98 kDa

Observed MW.

98 kDa

Uniprot ID

Q05193, P39053, P21575



Applications

Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 1000-1: 2000

brain, cerebral cortex,

cerebellum

IHC

Mouse, Rat

1: 300-1: 600

brain

IF

Mouse, Rat

1: 150-1: 300

brain



Background

This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15.


Images

image.png

Western blot analysis of Dynamin 1

(GB11855) at dilution of 1: 1000

Lane 1: Human brain tissue lysate

Lane 2: Mouse brain tissue lysate

Lane 3: Mouse cerebral cortex tissue lysate

Lane 4: Mouse cerebellum tissue lysate

Lane 5: Rat brain tissue lysate

Lane 6: Rat cerebral cortex tissue lysate

Lane 7: Rat cerebellum tissue lysate

image.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using

Dynamin 1 (GB11855) at dilution of 1: 500



Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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