PHONE

+86(027) 5111 3188

Share to:

Anti -Gemin 2 Rabbit pAb

  • Servicebio

Description

Download Attachment Files
Attachment Download Address: ×
/e/DownSys/DownSoft/?classid=285&id=5210&pathid=0

Product Information

Description

Gemin 2 rabbit polyclonal

Protein full name

Gem-associated protein 2

Synonyms

Gemin2, GEMIN2, SIP1, SIP1-delta, Survival of motor neuron protein-interacting protein 1, gem nuclear organelle associated protein 2

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Gemin 2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Predicted MW.

30 kDa

Observed MW.

30 kDa

Uniprot ID

O14893, Q9CQQ4



Applications

Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

muscle, testis

IHC

Mouse, Rat

1: 1000-1: 2000

lung, testis, bone,

spinal cord

IF

Mouse, Rat

1: 500-1: 1000

lung, testis, bone,

spinal cord



Background

This gene encodes one of the proteins found in the SMN complex, which consists of several gemini proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.


Images

image.png

Western blot analysis of Gemin 2

(GB11862) at dilution of 1: 1000

Lane 1: HepG2 cell lysate

Lane 2: 293T cell lysate

Lane 3: Jurkat cell lysate

Lane 4: HeLa cell lysate

Lane 5: NIH/3T3 cell lysate

Lane 6: Mouse muscle tissue lysate

Lane 7: Rat muscle tissue lysate

Lane 8: Rat testis tissue lysate


image.png

Immunohistochemistry analysis of paraffin-embedded rat lung using

Gemin 2 (GB11862) at dilution of 1: 1000


image.png

Immunohistochemistry analysis of paraffin-embedded mouse testis using

Gemin 2 (GB11862) at dilution of 1: 1000


image.png

Immunohistochemistry analysis of paraffin-embedded rat testis using

Gemin 2 (GB11862) at dilution of 1: 1000


image.png

Immunohistochemistry analysis of paraffin-embedded mouse bone using

Gemin 2 (GB11862) at dilution of 1: 1000


image.png

Immunohistochemistry analysis of paraffin-embedded rat spinal cord using

Gemin 2 (GB11862) at dilution of 1: 1000



Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

Contact us

Quick Links

Product Category

Get In Touch

 5th Floor, 22 Building, Biopark, Gaoxin 2nd Road No. 388, East Lake High-Tech Developing Zone, Wuhan, Hubei, China 430079
 +86(027) 5111 3188
Copyright © 2021  Wuhan Servicebio Technology Co., Ltd.