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Anti -Hexokinase II Rabbit pAb

  • Servicebio

Description

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Product Information

Description

Hexokinase II rabbit polyclonal

Protein full name

Hexokinase-2

Synonyms

HK2, HKII, HXK2, Hexokinase 2, Hexokinase type II,Muscle form hexokinase

Immunogen

Recombinant protein corresponding to Mouse Hexokinase II

Isotype

IgG

Purity

Affinity purification

Predicted MW.

103 kDa

Observed MW.

103 kDa

Uniprot ID

O08528, P27881



Applications

Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 1000

heart, muscle



Background

Hexokinase 2 also known as HK2 is an enzyme which in humans is encoded by the HK2 gene on chromosome 2.In particular, HK2 is ubiquitously expressed in tissues, though it is majorly found in muscle and adipose tissue. In cardiac and skeletal muscle, HK2 can be found bound to both the mitochondrial and sarcoplasmic membrane. The HK2 gene expression is regulated by a phosphatidylinositol 3-kinaselp70 S6 protein kinase-dependent pathway and can be induced by factors such as insulin, hypoxia, cold temperatures, and exercise. Its inducible expression indicates its adaptive role in metabolic responses to changes in the cellular environment.


Images

image.png

Western blot analysis of Hexokinase II

(GB11866) at dilution of 1: 1000

Lane 1: Mouse heart tissue lysate

Lane 2: Mouse muscle tissue lysate

Lane 3: Rat heart tissue lysate

Lane 4: Rat muscle tissue lysate



Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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