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GB11867 Anti -MMP8 Rabbit pAb Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse MMP8
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11867
  • Servicebio

Description

Product Information


Description

MMP8 rabbit polyclonal

Protein full name

Neutrophil collagenase

Synonyms

Mmp8, MMP8, CLG1, HNC, MMP-8, PMNL-CL, Matrix metallopeptidase 8

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse MMP8

Isotype

IgG

Purity

Affinity purification

Predicted MW.

54 kDa

Observed MW.

72 kDa

Uniprot ID

P22894, O70138, O88766




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

testis, ovary, uterus




Background


Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens.




Images



image.png

Western blot analysis of MMP8

(GB11867) at dilution of 1: 1000

Lane 1: A549 cell lysate

Lane 2: Jurkat cell lysate

Lane 3: NIH/3T3 cell lysate

Lane 4: Mouse testis tissue lysate

Lane 5: Mouse ovary tissue lysate

Lane 6: Mouse uterus tissue lysate

Lane 7: Rat testis tissue lysate

Lane 8: Rat ovary tissue lysate

Lane 9: Rat uterus tissue lysate





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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