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Anti -KSR1 Rabbit pAb

  • Servicebio

Description

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Product Information

Description

KSR1 rabbit polyclonal

Protein full name

Kinase suppressor of Ras 1

Synonyms

mKSR1, Protein Hb, Ksr1, Ksr, BKSR1, EK31, RSU2, SR31, Suppressor of Ras1 31

Immunogen

Recombinant protein corresponding to Mouse KSR1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

97 kDa

Observed MW.

97 kDa

Uniprot ID

Q8IVT5



Applications

Applications

Species

Dilution

Positive Tissue

WB

Human

1: 500-1: 1000

Hek293, HeLa, U251



Background


KSR1 is a molecular scaffold and positive regulator of the Raf/MEK/ERK phosphorylation cascade. It was initially considered to be a protein kinase acting in the Ras pathway. KSR1 is required for maximal ERK activation induced by growth factors and by some cytotoxic agents. In resting cells, phosphorylated KSR1 is cytoplasmic and in stimulated cells, dephosphorylated KSR1 is membrane associated.


Images

image.png

Western blot analysis of KSR1

(GB11878) at dilution of 1: 1000

Lane 1: Hek293 cell lysate

Lane 2: HeLa cell lysate

Lane 3: U251 cell lysate


Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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