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GB11879 Anti -CK1 epsilon Rabbit pAb Antibody

Immunogen: Recombinant protein corresponding to Mouse CK1 epsilon
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11879
  • Servicebio

Description

Product Information


Description

CK1 epsilon rabbit polyclonal

Protein full name

Casein kinase I isoform epsilon

Synonyms

Csnk1e, Casein kinase 1 epsilon, Casein kinase I, CKI epsilon, CSNK1E, DBT, KC1E

Immunogen

Recombinant protein corresponding to Mouse CK1 epsilon

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm

Predicted MW.

47 kDa

Observed MW.

47 kDa

Uniprot ID

P49674, Q9JMK2




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

lung, heart,

cerebral cortex

IHC

Human

1: 1500-1: 3000

lung cancer,

colon cancer

IF

Human

1: 500-1: 1500

lung cancer,

colon cancer




Background


Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm. Inhibits cytokine-induced granuloytic differentiation.




Images


Western blot analysis of CK1 epsilon

(GB11879) at dilution of 1: 1000

Lane 1: A431 cell lysate

Lane 2: 293T cell lysate

Lane 3: Mouse lung tissue lysate

Lane 4: Mouse cerebral cortex tissue lysate

Lane 5: Rat heart tissue lysate

Lane 6: Rat lung tissue lysate

Lane 7: Rat cerebral cortex tissue lysate


Immunohistochemistry analysis of paraffin-embedded human lung cancer using

CK1 epsilon (GB11879) at dilution of 1: 3000


Immunohistochemistry analysis of paraffin-embedded human colon cancer using CK1 epsilon (GB11879) at dilution of 1: 3000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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