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GB11884 Anti -Filamin A Rabbit pAb Anitbody

Immunogen: Recombinant protein corresponding to Mouse Filamin A
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11884
  • Servicebio

Description

Product Information


Description

Filamin A rabbit polyclonal

Protein full name

Filamin-A

Synonyms

Flna, FLNA, ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD, Filamin A, FGS2

Immunogen

Recombinant protein corresponding to Mouse Filamin A

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm

Predicted MW.

282 kDa

Observed MW.

282 kDa

Uniprot ID

P21333, Q8BTM8




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse

1: 500-1: 1000

liver

IHC

Mouse, Rat

1: 1000-1: 2000

liver, heart

IF

Mouse, Rat

1: 500-1: 1000

liver, heart




Background


Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking.




Images


Western blot analysis of Filamin A

(GB11884) at dilution of 1: 1000

Lane 1: Jurkat cell lysate

Lane 2: U251 cell lysate

Lane 3: Mouse liver tissue lysate


Immunohistochemistry analysis of paraffin-embedded mouse liver using

Filamin A (GB11884) at dilution of 1: 1000


Immunohistochemistry analysis of paraffin-embedded mouse heart using

Filamin A (GB11884) at dilution of 1: 1000


Immunohistochemistry analysis of paraffin-embedded rat heart using

Filamin A (GB11884) at dilution of 1: 1000





Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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