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GB11902 Anti -ATP citrate lyase Rabbit pAb Antibody

Immunogen: Recombinant protein corresponding to Mouse ATP citrate lyase
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11902
  • Servicebio

Description

Product Information



Description

ATP citrate lyase rabbit polyclonal

Protein full name

ATP-citrate synthase

Synonyms

Acly, ACL, ATP citrate lyase, ATP citrate synthase, ATPCL, Citrate cleavage enzyme, CLATP, ATP-citrate (pro-S-)-lyase

Immunogen

Recombinant protein corresponding to Mouse ATP citrate lyase

Isotype

IgG

Purity

Affinity purification

Predicted MW.

120 kDa

Observed MW.

120 kDa

Uniprot ID

P53396, Q91V92, P16638




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

cerebral cortex,

fat, brain




Background


ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.




Images



image.png

Western blot analysis of ATP citrate lyase

(GB11902) at dilution of 1: 1000

Lane 1: LNCAP cell lysate

Lane 2: MCF7 cell lysate

Lane 3: HEK293 cell lysate

Lane 4: Mouse fat tissue lysate

Lane 5: Mouse cerebral cortex tissue lysate

Lane 6: Mouse brain tissue lysate

Lane 7: Rat fat tissue lysate

Lane 8: Rat brain tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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