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GB11917 Anti -PDX1 Rabbit pAb Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse PDX1
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11917
  • Servicebio

Description

Product Information



Description

PDX1 rabbit polyclonal

Protein full name

Pancreas/duodenum homeobox protein 1

Synonyms

Pdx1, PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PAGEN1, PDX-1, STF-1, Pancreatic and duodenal homeobox 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse PDX1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

31 kDa

Observed MW.

42 kDa

Uniprot ID

P52945, P52946, P52947




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

spleen,

pancreas, colon




Background


Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.




Images



image.png

Western blot analysis of PDX1

(GB11917) at dilution of 1: 1000

Lane 1: PANC1 cell lysate

Lane 2: HPAC cell lysate

Lane 3: SW1990 cell lysate

Lane 4: Mouse spleen tissue lysate

Lane 5: Mouse pancreas tissue lysate

Lane 6: Rat pancreas tissue lysate

Lane 7: Rat colon tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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