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GB11934 Anti -RASGRP3 Rabbit Polyclonal Antibody

Immunogen: Recombinant protein corresponding to Human RASGRP3
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11934
  • Servicebio

Description

Product Information


Description

RASGRP3 rabbit polyclonal

Protein full name

Ras guanyl-releasing protein 3

Synonyms

RASGRP3, RASGRP3, GRP3,

RAS guanyl releasing protein 3

Immunogen

Recombinant protein corresponding to

Human RASGRP3

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane

Predicted MW.

78 kDa

Observed MW.

78 kDa

Uniprot ID

Q6NZH9




Applications


Applications

Species

Dilution

Positive Tissue

WB

Rat

1: 500-1: 1000

liver, kidney

IHC

Mouse, Rat

1: 300-1: 600

brain

IF

Mouse, Rat

1: 150-1: 300

brain




Background


Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation.




Images


image.png

Western blot analysis of RASGRP3 (GB11934) at dilution of 1: 1000

Lane 1:Rat liver tissue lysate

Lane 2: Rat kidney tissue lysate

image.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using RASGRP3 (GB11934) at dilution of 1: 1000

image.png

Immunohistochemistry analysis of paraffin-embedded rat brain using RASGRP3 (GB11934) at dilution of 1: 1000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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