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GB11935 Anti -LAMTOR2 Rabbit Plyclonal Antibody

Immunogen: Recombinant protein corresponding to Mouse LAMTOR2
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11935
  • Servicebio

Description

Product Information


Description

LAMTOR2 rabbit polyclonal

Protein full name

Ragulator complex protein LAMTOR2

Synonyms

Lamtor2, ENDAP, Endosomal adaptor protein p14, MAPBPIP, MAPKSP1AP, P14, ROBLD 3

Immunogen

Recombinant protein corresponding to Mouse LAMTOR2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm

Uniprot ID

Q9JHS3




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 500-1: 1500

brain, lung, stomach

IF

Mouse, Rat

1: 250-1: 500

brain, lung, stomach




Background


As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.




Images


image.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using LAMTOR2 (GB11935) at dilution of 1: 1000

image.png

Immunohistochemistry analysis of paraffin-embedded rat brain using LAMTOR2 (GB11935) at dilution of 1: 1000

image.png

Immunohistochemistry analysis of paraffin-embedded mouse lung using LAMTOR2 (GB11935) at dilution of 1: 1000

image.png

Immunohistochemistry analysis of paraffin-embedded rat lung using LAMTOR2 (GB11935) at dilution of 1: 1500

image.png

Immunohistochemistry analysis of paraffin-embedded mouse stomach using LAMTOR2 (GB11935) at dilution of 1: 1500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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