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GB11941 Anti -MRP1 Rabbit pAb Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Human MRP1
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11941
  • Servicebio

Description

Product Information


Description

MRP1 rabbit polyclonal

Protein full name

Multidrug resistance-associated protein 1

Synonyms

ATP-binding cassette sub-family C member 1, Leukotriene C(4) transporter, ABCC1, MRP1, ABCC, LTC4 transporter, ABC29, ABCC 1, GSX, Multidrug resistance associated protein 1, Multidrug resistance protein, MRP, Multiple drug resistance protein 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Human MRP1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane

Uniprot ID

P33527




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human

1: 1000-1: 2000

lung cancer, stomach

IF

Human

1: 500-1: 1000

lung cancer, stomach




Background


Multidrug resistance-associated protein 1 (MRP1) is a protein that in humans is encoded by the ABCC1 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.




Images


image.png

Immunohistochemistry analysis of paraffin-embedded human lung cancer using MRP1 (GB11941) at dilution of 1: 1000

image.png

Immunohistochemistry analysis of paraffin-embedded human stomach using MRP1 (GB11941) at dilution of 1: 1000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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