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GB11946 Anti -ADRM1/ARM-1 Rabbit Polyclonal Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse ADRM1
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11946
  • Servicebio

Description

Product Information


Description

ADRM1 rabbit polyclonal

Protein full name

Proteasomal ubiquitin receptor ADRM1

Synonyms

110 kDa cell membrane glycoprotein, Gp110, Adhesion-regulating molecule 1, ARM-1, Rpn13 homolog, Adrm1, M(r) 110,000 surface antigen, Proteasomal ubiquitin receptor ADRM1, proteasome regulatory particle non ATPase 13, Rpn13

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse ADRM1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

42 kDa

Observed MW.

42 kDa

Uniprot ID

Q16186, Q9JKV1, Q9JMB5




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

testis, ovary




Background


ADRM1 is a 407 amino acid protein that localizes to both the nucleus and the cytoplasm and is thought to be involved in protein recruitment and cell adhesion. An integral membrane protein, ADRM1 functions to recruit UCH-L5, a deubiquitinating enzyme, to the 26S proteasome, and once at the proteasome it promotes the activity of UCH-L5. Additionally, ADRM1 is thought to mediate lymphocyte adhesion in endothelial cells and may thus play a role in lymphocyte homing. ADRM1 expression is induced by IFN-g in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis. Two isoforms of ADRM1 exist due to alternative splicing events.




Images


image.png

Western blot analysis of ADRM1 (GB11946) at dilution of 1: 1000

Lane 1: HepG2 cell lysate

Lane 2: A549 cell lysate

Lane 3: MCF7 cell lysate

Lane 4: Raw264.7 cell lysate

Lane 5: Mouse testis tissue lysate

Lane 6: Mouse ovary tissue lysate

Lane 7: Rat testis tissue lysate

Lane 8: Rat ovary tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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