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GB11950 Anti -Annexin-7/ANXA7 Rabbit pAb Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Annexin-7
Isotype: IgG
Purity: Affinity purification
  • GB11950
  • Servicebio


Product Information


Annexin-7 rabbit polyclonal

Protein full name

Annexin A7


Annexin VII, Annexin-7, Synexin, Anxa7, Anx7, AnnexinVII, SNX


KLH conjugated Synthetic peptide corresponding to Mouse Annexin-7




Affinity purification

Predicted MW.

50 kDa

Observed MW.

50 kDa

Uniprot ID

P20073, Q07076, Q6IRJ7





Positive Tissue


Human, Mouse, Rat

1: 500-1: 1000

heart, lung


ANXA7 is a member of the annexin family of calcium/phospholipid-binding proteins, and is involved in the process of membrane fusion and exocytosis . Annexin A7 is a GTPase, and both GTPbinding and PKC activity are important in regulating protein function . Membrane binding of annexin A7 is calcium dependent . Two isoforms exist due to alternative splicing. Subcellular localization of annexin A7 has been shown to be in the cytoplasm, vesicular structures, membrane and in adrenal chromaffin granules . Nuclear localization has been shown in the developing mouse central nervous system as well as in adult mouse brain . Annexin A7- deficient mouse studies show that the protein has a role in insulin secretion and calcium signaling as well as cardiac intracellular calcium homeostasis electrical stability . The gene for annexin A7 is a putative tumor suppressor , and alterations in the copy number have been reported in prostate cancer . Annexin A7 expression has alsobeen correlated with survival in human glioblastoma patients , and haploinsufficiency in mice may promote genetic instability leading to tumorigenesis .



Western blot analysis of Annexin-7 (GB11950) at dilution of 1: 1000

Lane 1: U87 cell lysate

Lane 2: PC3 cell lysate

Lane 3: NIH/3t3 cell lysate

Lane 4: PC12 cell lysate

Lane 5: Mouse heart tissue lysate

Lane 6: Mouse lung tissue lysate

Lane 7: Rat heart tissue lysate

Lane 8: Rat lung tissue lysate


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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