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GB11953 Anti -Cadherin 16 Rabbit PAb Primary Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Cadherin 16
Isotype: IgG
Purity: Apurification
ul:
  • GB11953
  • Servicebio

Description

Product Information


Description

Cadherin 16 rabbit polyclonal

Protein full name

Cadherin-16

Synonyms

Kidney-specific cadherin, Ksp-cadherin, Cdh16, Cadherin kidney

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Cadherin 16

Isotype

IgG

Purity

Apurification

Subcellular location

Cell membrane

Predicted MW.

90 kDa

Observed MW.

130 kDa

Uniprot ID

O88338, G3V7L4




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse

1: 500-1: 1000

kidney

IHC

Mouse, Rat

1: 500-1: 1000

kidney

IF

Mouse, Rat

1: 250-1: 500

kidney




Background


This gene is a member of the cadherin super family, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with super family members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.




Images


image.png

Western blot analysis of Cadherin 16 (GB11953) at dilution of 1: 1000

Lane 1: Mouse kidney tissue lysate

Lane 2: Mouse kidney tissue lysate

Lane 3: Mouse kidney tissue lysate

Lane 4: Mouse kidney tissue lysate

image.png

Immunohistochemistry analysis of paraffin-embedded mouse kidney using Cadherin 16 (GB11953) at dilution of 1: 1000

image.png

Immunohistochemistry analysis of paraffin-embedded rat kidney using Cadherin 16 (GB11953) at dilution of 1: 1000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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