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GB11956 Anti -Aldolase Rabbit Polyclonal Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Aldolase
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11956
  • Servicebio

Description

Product Information


Description

Aldolase rabbit polyclonal

Protein full name

Fructose-bisphosphate aldolase A

Synonyms

Aldolase 1, Muscle-type aldolase, Aldoa, Aldo1, Aldolase A, Fructose 1 6 bisphosphate triosephosphate lyase, GSD12, Lung cancer antigen NY LU 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Aldolase

Isotype

IgG

Purity

Affinity purification

Predicted MW.

39 kDa

Observed MW.

39 kDa

Uniprot ID

P05064, P05065




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

muscle, brain, heart




Background



Aldolase A (fructose bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3 phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Research studies suggest that Aldolase A is upregulated in various cancers, including human lung squamous and renal cell carcinomas. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode the same protein.




Images


image.png

Western blot analysis of Aldolase (GB11956) at dilution of 1: 1000

Lane 1: L929 cell lysate

Lane 2: NIH/3t3 cell lysate

Lane 3: Mouse muscle tissue lysate

Lane 4: Mouse brain tissue lysate

Lane 5: Mouse heart tissue lysate

Lane 6: Rat muscle tissue lysate

Lane 7: Rat brain tissue lysate

Lane 8: Rat heart tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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