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GB11963 Anti -Integrin Linked ILK Rabbit Polyclonal Antibody

Immunogen: Recombinant protein corresponding to Mouse Integrin linked ILK
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11963
  • Servicebio

Description

Product Information


Description

Integrin linked ILK rabbit polyclonal

Protein full name

Integrin-linked protein kinase

Synonyms

Ilk, 59 kDa serine/threonine-protein kinase, epididymis secretory protein Li 28, ILK-1, P59, kinase-2, integrin-linked kinase, integrin-linked ILK-2, Integrin-linked protein kinase, p59ILK

Immunogen

Recombinant protein corresponding to Mouse Integrin linked ILK

Isotype

IgG

Purity

Affinity purification

Predicted MW.

51 kDa

Observed MW.

51 kDa

Uniprot ID

Q13418, O55222, Q99J82




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

lung, uterus,

heart, liver




Background


This Integrin-linked kinase (ILK) gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. This protein belongs to the protein kinase super family. It can be autophosphorylated on serine residues. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.




Images


image.png

Western blot analysis of Integrin linked ILK (GB11963) at dilution of 1: 1000

Lane 1: A549 cell lysate

Lane 2: Mouse lung tissue lysate

Lane 3: Mouse uterus tissue lysate

Lane 4: Mouse heart tissue lysate

Lane 5: Mouse liver tissue lysate

Lane 6: Rat lung tissue lysate

Lane 7: Rat uterus tissue lysate

Lane 8: Rat heart tissue lysate

Lane 9: Rat liver tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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