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Anti -ACSS2 Rabbit PAb for IHC IF Primary Antibody

Specification: 100uL
  • GB11967
  • Servicebio
  • Servicebio

Description

Product Information


Description

ACSS2 rabbit polyclonal

Protein full name

Acetyl-coenzyme A synthetase, cytoplasmic

Synonyms

AceCS, ACSS2, ACAS2, Acyl-activating enzyme, Acetate--CoA ligase, Acetyl-CoA synthetase,

ACS, Acyl-CoA synthetase short-chain family member 2, ACSA

Immunogen

Recombinant protein corresponding to Mouse ACSS2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm

Uniprot ID

Q9NR19




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human

1: 500-1: 1000

kidney, liver

IF

Human

1: 250-1: 500

kidney, liver




Background


ACSS2 (acyl-CoA synthetase short-chain family member 2), also known as ACAS2, ACS, ACSA or AceCS, is a 701 amino acid cytoplasmic protein that belongs to the ATP-dependent AMP-binding enzyme family. Existing as a monomer, ACSS2 functions to catalyze the ATP-dependent activation of acetate, a reaction that yields acetyl-CoA for use in energy generation and lipid synthesis. ACSS2 expression, which is highest in liver and kidney tissue, is regulated by the presence of unsaturated fatty acids and sterol regulatory element-binding proteins (SREBPs). Human ACSS2 exists as two alternatively spliced isoforms and shares 93% sequence identity with its mouse counterpart, suggesting a conserved role between species.




Images


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Immunohistochemistry analysis of paraffin-embedded human lung cancer using ACSS2 (GB11967) at dilution of 1: 500

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Immunohistochemistry analysis of paraffin-embedded human ovarian cancer using ACSS2 (GB11967) at dilution of 1: 500

image.png

Immunohistochemistry analysis of paraffin-embedded human stomach using ACSS2 (GB11967) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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