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Anti -mSin3A Rabbit pAb for IHC IF

Specification: 100uL
  • GB11968
  • Servicebio
  • Servicebio

Description

Product Information


Description

mSin3A rabbit polyclonal

Protein full name

Paired amphipathic helix protein Sin3a

Synonyms

Histone deacetylase complex subunit Sin3a, Transcriptional corepressor Sin3a, Kiaa4126

Immunogen

Recombinant protein corresponding to Mouse mSin3A

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

Q60520, D3ZBP2




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 100-1: 200

colon, kidney, heart, testicle, ovary

IF

Mouse, Rat

1: 100-1: 200

colon, kidney, heart, testicle, ovary




Background


The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex. And It acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation.




Images


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Immunohistochemistry analysis of paraffin-embedded mouse colon using mSin3A (GB11968) at dilution of 1: 100

image.png

Immunohistochemistry analysis of paraffin-embedded mouse kidney using mSin3A (GB11968) at dilution of 1: 100

image.png

Immunohistochemistry analysis of paraffin-embedded mouse heart using mSin3A (GB11968) at dilution of 1: 100

image.png

Immunohistochemistry analysis of paraffin-embedded rat testis using mSin3A (GB11968) at dilution of 1: 100

image.png

Immunohistochemistry analysis of paraffin-embedded rat ovary using mSin3A (GB11968) at dilution of 1: 100




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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