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Anti -CD99 Rabbit PAb for Western Blot

Specification: 100uL
  • GB11970
  • Servicebio
  • Servicebio

Description

Product Information


Description

CD99 rabbit polyclonal

Protein full name

CD99 antigen

Synonyms

12E7, MIC2, MIC2X, MIC2Y, E2 antigen, CD99,

Protein MIC2, T-cell surface glycoprotein E2,

HBA71, CD99-H

Immunogen

KLH conjugated Synthetic peptide

corresponding to Human CD99

Isotype

IgG

Purity

Affinity purification

Predicted MW.

19 kDa

Observed MW.

32 kDa

Uniprot ID

P14209




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human

1: 500-1: 1000

Jurkat, THP-1, HUVEC




Background


CD99, also known as MIC2, is a heavily O-glycosylated transmembrane protein involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. CD99 is broadly distributed on many cell types, with particularly strong expression on human cortical thymocytes, Ewing’s sarcoma cells and peripheral primitive neuroectodermal tumors . In normal cells, CD99 has been functionally implicated in cell adhesion, migration, apoptosis, differentiation, activation, and proliferation of lymphocytes and monocyte extravasation and transport of several transmembrane proteins .CD99 is expressed in many types of tumors and has been used for differential diagnosis of conventional Ewing sarcoma. It has been actively pursued as a therapeutic target. On the other hand, CD99 may also play a tumor suppressor role in other tumors, such as Hodgkin’s lymphomas, osteosarcomas, and pancreatic tumors.




Images


image.png

Western blot analysis of CD99 (GB11970) at dilution of 1: 1000

Lane 1: Jurkat cell lysate

Lane 2: THP-1 cell lysate

Lane 3: HUVEC cell lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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