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Anti -Mark3 Rabbit PAb for Western Blot

Specification: 100uL
  • GB11976
  • Servicebio
  • Servicebio

Description

Product Information


Description

Mark3 rabbit polyclonal

Protein full name

MAP/microtubule affinity-regulating kinase 3

Synonyms

cTAK1, Cdc25C-associated protein kinase 1, ELKL motif kinase 2, EMK-2, Protein kinase STK10, Ser/Thr protein kinase PAR-1, Par-1a, Serine/threonine-protein kinase p78, Mark3, EMK2/MARK3 serine-threonine protein kinase, MPK-10, serine/threonine kinase 10

Immunogen

Recombinant protein corresponding to Human Mark3

Isotype

IgG

Purity

Affinity purification

Predicted MW.

84 kDa

Observed MW.

84 kDa

Uniprot ID

Q8VHF0




Applications


Applications

Species

Dilution

Positive Tissue

WB

Rat

1: 500-1: 1000

lung, kidney, stomach




Background


Serine/threonine-protein kinase . Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU . Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus . Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1.




Images


image.png

Western blot analysis of Mark3 (GB11976) at dilution of 1: 1000

Lane 1: Rat lung tissue lysate

Lane 2: Rat kidney tissue lysate

Lane 3: Rat stomach tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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