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Anti -Rel B Rabbit PAb for WB IHC IF Polyclonal Antibody

Specification: 100uL
  • GB11985
  • Servicebio
  • Servicebio

Description

Product Information


Description

Rel B rabbit polyclonal

Protein full name

Transcription factor RelB

Synonyms

Reticuloendotheliosis viral oncogene homolog B, Nuclear factor of kappa light polypeptide gene enhancer in B cells 3, IREL, v rel avian reticuloendotheliosis viral oncogene homolog

Immunogen

Recombinant protein corresponding to Mouse Rel B

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Predicted MW.

60 kDa

Observed MW.

70 kDa

Uniprot ID

Q01201, Q04863, Q9EQX9




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1:500-1:1000

kidney, colon

IHC

Human

1: 1000-1: 2000

colon cancer,

stomach cancer

IF

Human

1: 1000-1: 2000

colon cancer,

stomach cancer




Background


RelB is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF- kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.




Images


image.png

Western blot analysis of Rel B (GB11985) at dilution of 1: 1000

Lane 1: Raji cell lysate

Lane 2: Jurkat cell lysate

Lane 3: A549 cell lysate

Lane 4: NIH/3T3 cell lysate

Lane 5: Raw264.7 cell lysate

Lane 6: Mouse kidney tissue lysate

Lane 7: Mouse colon tissue lysate

Lane 8: Rat kidney tissue lysate

Lane 9: Rat colon tissue lysate

image.png

Immunohistochemistry analysis of paraffin-embedded human colon cancer using Rel B (GB11985) at dilution of 1: 1000

image.png

Immunohistochemistry analysis of paraffin-embedded human stomach cancer using Rel B (GB11985) at dilution of 1: 1000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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