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Anti -CtBP1 Rabbit PAb for IHC IF Polyclonal Antibody

Specification: 100uL
  • GB11987
  • Servicebio
  • Servicebio

Description

Product Information


Description

CtBP1 rabbit polyclonal

Protein full name

C-terminal-binding protein 1

Synonyms

brefeldin A-ribosylated substrate, BARS, CTBP, MGC104684, C-terminal-binding protein 1, CtBP1

Immunogen

Recombinant protein corresponding to

Mouse CtBP1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Uniprot ID

Q13363, O88712, Q9Z2F5




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human, Mouse, Rat

1: 500-1: 1500

colon cancer, small intestine, brain, uterus

IF

Human, Mouse, Rat

1: 250-1: 750

colon cancer, small intestine, brain, uterus




Background


CTBP1 also named as C-terminal-binding protein 1 which belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. CTBP1 is a cellular phosphoprotein that associates with various proteins and functions as a corepressor of transcription.Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity. CTBP1 and the related protein CTBP2 are characterized as C-terminal binding protein of adenovirus E1A, and they preferentially associate with the E1A via a 5-amino acid motif, PLDLS, to repress E1A induced oncogenesis and cellular transformation. CTBP1 is expressed from embryo to adult, but CTBP2 is mainly expressed during embryogenesis.




Images


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Immunohistochemistry analysis of paraffin-embedded human colon cancer using CtBP1 (GB11987) at dilution of 1: 1000

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Immunohistochemistry analysis of paraffin-embedded mouse small intestine using CtBP1 (GB11987) at dilution of 1: 1000

image.png

Immunohistochemistry analysis of paraffin-embedded rat brain using CtBP1 (GB11987) at dilution of 1: 1000

image.png

Immunohistochemistry analysis of paraffin-embedded rat uterus using CtBP1 (GB11987) at dilution of 1: 1000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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