PHONE

+86(027) 5111 3188

Share to:

Anti -TBC1D7 Rabbit PAb for Western Blot

Specification: 100uL
  • GB11990
  • Servicebio
  • Servicebio

Description

Product Information


Description

TBC1D7 rabbit polyclonal

Protein full name

TBC1 domain family member 7

Synonyms

Tbc1d7, cell migration-inducing protein 23, dJ257A7.3, DKFZp686N2317, FLJ32666, PIG51, TBC1 domain family member 7, TBC7, TCD1D7

Immunogen

Recombinant protein corresponding to Mouse TBC1D7

Isotype

IgG

Purity

Affinity purification

Predicted MW.

34 kDa

Observed MW.

36 kDa

Uniprot ID

Q9P0N9, Q9D0K0, D4AAY4




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human,

Mouse, Rat

1: 500-1: 1000

prostate, testis, brain




Background


TBC1 domain family member 7 (TBC1D7, TBC7) belongs to a family of TBC (Tre-2/Bub2/Cdc16) containing proteins that function as GTPase-activating proteins (GAPs) . TBC1D7 was initially identified as a novel binding protein within the TSC1-TSC2 complex, where it was thought to associate with TSC1 . Additional research indicates that TBC1D7 is a third subunit of the TSC1-TSC2 complex that possesses Rheb-GAP activity and signals upstream of mTORC1. Knockdown of TBC1D7 limits the association between TSC1 and TSC2, resulting in reduced Rheb-GAP activity and increased mTORC1 signaling . Mutations in the corresponding TBC1D7 gene result in increased mTORC1 signaling, delayed autophagy, and are associated with intellectual disability (ID) and macrocrania.




Images


image.png

Western blot analysis of TBC1D7 (GB11990) at dilution of 1: 1000

Lane 1: Hela cell lysate

Lane 2: K562 cell lysate

Lane 3: NIH3T3 cell lysate

Lane 4: Mouse prostate tissue lysate

Lane 5: Mouse testis tissue lysate

Lane 6: Mouse brain tissue lysate

Lane 7: Rat prostate tissue lysate

Lane 8: Rat testis tissue lysate

Lane 9: Rat brain tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

downLoadImgSlice 13Laboratory(1)Slice 10Slice 12

Contact us

Quick Links

Product Category

Get In Touch

 5th Floor, 22 Building, Biopark, Gaoxin 2nd Road No. 388, East Lake High-Tech Developing Zone, Wuhan, Hubei, China 430079
 +86(027) 5111 3188
Copyright © 2021  Wuhan Servicebio Technology Co., Ltd.