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Anti -beta Catenin Mouse mAb for WB IHC IF

Specification: 100uL
  • GB12015
  • Servicebio
  • Servicebio

Description

Product Information


Description

beta Catenin mouse monoclonal

Protein full name

Catenin beta-1

Synonyms

CTNNB1, CTNNB, MRD19, armadillo, catenin beta 1

Immunogen

Recombinant protein corresponding to Mouse β-catenin

Isotype

IgG

Predicted MW.

92 kDa

Observed MW.

92 kDa

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus, Cell junction,

Cell membrane

Uniprot ID

P35222, Q02248, Q9WU82




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

lung, kidney

IHC

Human, Mouse, Rat

1: 100-1: 500

stomach

IF

Human, Mouse, Rat

1: 100-1: 500

stomach




Background



β-catenin is a dual function protein, involved in regulation and coordination of cell–cell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. β-catenin is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and homologous to γ-catenin, also known as plakoglobin. Beta-catenin is widely expressed in many tissues. In cardiac muscle, beta-catenin localizes to adherens junctions in intercalated disc structures, which are critical for electrical and mechanical coupling between adjacent cardiomyocytes.




Images



GB12015.png

Western blot analysis of β-catenin (GB12015) at dilution of 1: 1000.

Lane 1: Mouse lung tissue lysate

Lane 2: Mouse kidney tissue lysate

Lane 3: Rat kidney tissue lysate

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Immunohistochemistry analysis of paraffin-embedded mouse stomach using β-catenin (GB12015)at dilution of 1:200


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Immunohistochemistry analysis of paraffin-embedded rat stomach using β-catenin (GB12015)at dilution of 1:200




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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