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Anti -CD105 Mouse MAb for Western Blot

Specification: 100uL
  • GB12020
  • Servicebio
  • Servicebio

Description

Product Information


Description

CD105 mouse monoclonal

Protein full name

Endoglin

Synonyms

Cell surface MJ7/18 antigen, CD105, Eng, Edg, FLJ41744, HHT1, ORW, ORW1

Immunogen

Recombinant protein corresponding to

Mouse CD105

Isotype

IgG

Purity

Affinity purification

Predicted MW.

70 kDa

Observed MW.

95 kDa

Uniprot ID

Q63961




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse

1: 500-1: 1000

kidney, liver, lung




Background


Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis.




Images


图片 1.png

Western blot analysis of CD105 (GB12020)

at dilution of 1: 1000

Lane 1: Mouse kidney tissue lysate

Lane 2: Mouse liver tissue lysate

Lane 3: Mouse lung tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

Laboratory(1)Slice 13downLoadImgSlice 10Slice 12

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