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Anti -ERK1+ ERK2 Mouse MAb Monoclonal Antibody for Western Blot

Specification: 100uL
  • GB12087
  • Servicebio
  • Servicebio

Description

Product Information



Description

ERK1+ ERK2 mouse monoclonal

Protein full name

Mitogen-activated protein kinase 1

Synonyms

MAPK1, ERK,ERK-2,ERK2, ERT1, MAPK2, P42MAPK,PRKM1,PRKM2,p38,p40,p41,p41mapk,p42-MAPK,mitogen-activated protein kinase 1

Immunogen

Recombinant protein corresponding to Mouse ERK2

Isotype IgG
Purity Affinity purification
Predicted MW.

42/44KDa

Observed MW.

42/44KDa

Uniprot ID

P63085,P63086,P28482,P27361,P21708,Q63844




Applications



Applications

WB

Species Human,Rat,Mouse
Dilution 1:1000
Positive tissue Hela,HepG2,NIH/3T3,lung,kidney,brain




Background



Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors.




Images



GB12087.png

Western blot analysis of ERK1/2 (GB12087) at dilution of 1:1000.

Lane 1:Hela cell lysate

Lane 2:HepG2 cell lysate

Lane 3:NIH/3T3 cell lysate

Lane 4:Mouse lung tissue lysate

Lane 5:Mouse kidney tissue lysate

Lane 6:Mouse brain tissue lysate

Lane 7:Rat lung tissue lysate

Lane 8:Rat kindy tissue lysate

Lane 9:Rat brain tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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