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GB12089 Anti -Fas Mouse Monoclonal Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse FAS
Isotype: IgG
Purity: Affinity purification
ul:
  • GB12089
  • Servicebio

Description

Product Information



Description

Fas mouse monoclonal

Protein full name

Tumor necrosis factor receptor superfamily member 6

Synonyms

FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, Fas cell surface death receptor

Immunogen KLH conjugated Synthetic peptide corresponding to Mouse FAS
Isotype IgG
Purity Affinity purification
Subcellular location

Cell membrane,Secrete

Uniprot ID

P25445,P25446




Applications


Applications

IHC,IF

Species

Human,Mouse

Dilution

1:200-1:800

Positive tissue

Gallbadder,colon




Background



Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).




Images



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Immunohistochemistry analysis of paraffin-embedded human gallbladder  using FAS (GB12089) at dilution of 1:200

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Immunohistochemistry analysis of paraffin-embedded mouse colon  using FAS (GB12089) at dilution of 1:400

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Immunohistochemistry analysis of paraffin-embedded mouse testis using FAS (GB12089) at dilution of 1:400




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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