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GB12104 Anti -Heme Oxygenase 1 Mouse Monoclonal Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse HMOX1
Isotype: IgG
Purity: Affinity purification
ul:
  • GB12104
  • Servicebio

Description

Product Information


Description

Heme Oxygenase 1 Mouse monoclonal

Protein full name

Heme oxygenase 1

Synonyms

HMOX1, HMOX1D, HO-1, HSP32, bK286B10,heme oxygenase 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse HMOX1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Endoplasmic reticulum

Predicted MW.

33 kDa

Observed MW.

33 kDa

Uniprot ID

P14901




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

spleen, liver, kidney

IHC

Mouse, Rat

1: 1000-1: 3000

spleen

IF

Mouse, Rat

1: 500-1: 1000

spleen




Background


Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.




Images



image.png

Western blot analysis of HMOX1

(GB12104) at dilution of 1: 1000

Lane 1: Raw264.7 cell lysate

Lane 2: Mouse spleen tissue lysate

Lane 3: Mouse liver tissue lysate

Lane 4: Mouse kidney tissue lysate

Lane 5: Mouse spleen tissue lysate

image.png

Immunohistochemistry analysis of paraffin-embedded mouse spleen using HMOX1 (GB11821) at dilution of 1: 1500

image.png

Immunohistochemistry analysis of paraffin-embedded rat spleen using HMOX1 (GB11821) at dilution of 1: 1500




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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