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GB12108 Anti -IL-10 Mouse Monoclonal Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse IL-10
Isotype: IgG
Purity: Affinity purification
ul:
  • GB12108
  • Servicebio

Description

Product Information


Description

Il-10 mouse monoclonal

Protein full name

Interleukin-10

Synonyms

IL10, CSIF, GVHDS, IL-10, IL10A, TGIF, interleukin 10, Cytokine Synthesis Inhibitory Factor, Interleukin-10 precursor

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse IL-10

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted

Uniprot ID

P29456




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Rat

1: 1000-1: 2000

lung, pneumonia

IF

Rat

1: 500-1: 1000

lung, pneumonia




Background



IL-10 is a cytokine with multiple, pleiotropic, effects in immunoregulation and inflammation. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-κB activity, and is involved in the regulation of the JAK-STAT signaling pathway.




Images



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Immunohistochemistry analysis of paraffin-embedded rat lung using IL-10 (GB12108) at dilution of 1: 2000.

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Immunohistochemistry analysis of paraffin-embedded rat pneumonia using IL-10 (GB12108) at dilution of 1: 1000.

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Immunofluorescence analysis of paraffin-embedded mouse Inflammatory lung using IL-10 (GB11108) at dilution of 1:300.

image.png

Immunofluorescence analysis of paraffin-embedded rat Inflammatory lung using IL-10 (GB11108) at dilution of 1:600.

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Immunofluorescence analysis of paraffin-embedded rat Inflammatory spleen using IL-10 (GB11108) at dilution of 1:600.




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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